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GGW101 (Lirucitinib) is a small molecule Janus kinase (JAK) inhibitor developed for veterinary use, specifically for the treatment of canine pruritus—a condition characterized by an unpleasant skin sensation that provokes scratching. The drug targets immune-mediated pathways involved in pruritus and has received regulatory approval in China as a Class I New Veterinary Drug for this indication. It was approved by the Ministry of Agriculture and Rural Affairs of China in October 2024 following successful clinical development, including a Phase I trial initiated in March 2022[3].
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