Drug intelligence / Profile preview

gibberellic acid

Development stage
Unknown
Modality
Small Molecules
Administration
Topical, Intravesical, Oral, Intravenous
01

Overview

Gibberellic acid is a naturally occurring plant hormone (gibberellin) and a pentacyclic diterpene acid that promotes growth and elongation of cells in plants. It acts as a plant growth regulator by stimulating both cell division and cell elongation, affecting leaves, stems, fruit development, seed germination rates, and overall plant maturation. Gibberellic acid exerts its effects by altering gene transcription through inhibition of pathway inhibitors (a double-negative mechanism), leading to increased mRNA production for hydrolytic enzymes during seed germination. Industrially produced using microorganisms such as Gibberella fujikuroi (from which it was first isolated in Japan in 1926), it is widely used in agriculture for crops and ornamental plants[1][4][5][6]. In animal studies (rats), it has shown biological activity including acting as an agonist of steroidogenesis[3].

Brand names
ProGibbBerelex
Other names
gibberellin A3GA3GA-3GA 3C19-gibberellin 6-carboxylic acidC-19-gibberellin 6-carboxylic acidC 19-gibberellin 6-carboxylic acid

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