Drug intelligence / Profile preview

ginger extract

Development stage
Phase 4
Modality
Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Ginger extract is a concentrated preparation derived from the rhizome of the Zingiber officinale plant. It contains a variety of bioactive compounds, most notably gingerols and shogaols, which are responsible for its characteristic flavor and many of its medicinal properties. Ginger extract has been used traditionally in herbal medicine for thousands of years to treat ailments such as nausea, vomiting, arthritis, migraines, hypertension, and digestive issues[1][3][4]. Modern research supports several potential health benefits including anti-inflammatory effects (by inhibiting cyclooxygenase-2 expression), antioxidant activity (scavenging free radicals), antimicrobial action against bacteria and viruses, cholesterol-lowering effects (reducing LDL oxidation), blood sugar regulation (enhancing GLUT4 expression), pain relief in conditions like osteoarthritis and dysmenorrhea, support for gastrointestinal motility (promoting gastric emptying), and possible chemopreventive properties[1][4][6][7]. The primary mechanisms involve modulation of inflammatory pathways and oxidative stress reduction. Ginger extract is available as a dietary supplement in various forms including capsules, powders, tinctures or standardized extracts.

Brand names
Pure Encapsulations Ginger Root Extract
Other names
gingerZingiber officinale extractginger root extract
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)SLC2A4 (Solute carrier family 2 facilitated glucose transporter member 4)

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