Drug intelligence / Profile preview

ginger mouthwash

Development stage
Unknown
Lead developer
Al-Mustansiriyah University
Modality
Small Molecules
Administration
Topical
01

Overview

Ginger mouthwash is a natural herbal oral rinse being investigated for its anti-inflammatory and antibacterial properties in the treatment of gingivitis. In a clinical trial led by Al-Mustansiriyah University, this specific formulation (manufactured by Pasta del Capitano) is being evaluated in pregnant women experiencing stress-related gingivitis. The mouthwash contains ginger (*Zingiber officinale*) extract and Sulfetal Zn® (Zinc Coco Sulphate). It aims to reduce clinical parameters such as the Plaque Index (PI), Gingival Index (GI), and Bleeding on Probing (BOP), while also modulating salivary biomarkers like Interleukin-6 (IL-6), cortisol, lactoferrin, and 8-hydroxy-2'-deoxyguanosine (8-OHdG).

Brand names
Pasta del Capitano Ginger Mouthwash
Other names
Zingiber officinale mouthwash
02

Targets

Gtf (Streptococcus mutans glucosyltransferase)Candida albicans biofilm and hyphal transition machinery

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