gingerol

Gingerol refers to a group of related phenolic compounds found in the rhizome of ginger (Zingiber officinale), with 6-gingerol being the major and most studied constituent. Gingerols are responsible for the pungent flavor of fresh ginger and are structurally characterized by a 4-hydroxy-3-methoxyphenyl group substituted at the C6 carbon atom by a hydroxyalkane ketone side chain. Gingerols exhibit various biological activities including anti-inflammatory, antioxidant, anticancer (antineoplastic), antifungal, and analgesic effects. Mechanistically, they modulate multiple cellular pathways involved in apoptosis (programmed cell death), inhibition of angiogenesis (formation of new blood vessels in tumors), cell cycle regulation, cytotoxicity against cancer cells, and free radical scavenging activity. Gingerol is not developed as a pharmaceutical drug but is widely studied for its potential therapeutic benefits as a natural product or dietary supplement[1][2][7].

Other names

6-gingerol[6]-gingerol[4]-gingerol10-gingerolrac-(R*)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)decane-3-one