Drug intelligence / Profile preview

ginkgo biloba + cistanche

Development stage
Unknown
Lead developer
Nutrilite
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

A combination of standardized extracts from Ginkgo biloba (leaf) and Cistanche tubulosa (root), used as a dietary supplement. This botanical blend has been studied for its potential to improve symptoms of chronic fatigue syndrome (CFS) and enhance cognitive function in healthy adults. Mechanistically, the combination is believed to exert antioxidant effects, reduce blood ammonia and lactic acid levels, promote neuronal growth, protect against cellular damage, and improve memory and executive function. The product is typically formulated with a higher proportion of Cistanche extract relative to Ginkgo extract (commonly 2.6–20:1 by weight). Clinical studies have shown improvements in fatigue scores, quality of life measures, sexual health indices in CFS patients[1][2], as well as enhancements in memory and cognitive flexibility in healthy adults[3]. The mechanism involves neuroprotection via antioxidative pathways and possible modulation of neurotransmitter systems.

Other names
Cistanche/ginkgo blendCGCistanche tubulosa and Ginkgo biloba combination
02

Targets

GHSR (Growth hormone secretagogue receptor)

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