Drug intelligence / Profile preview

ginseng berry concentrate

Development stage
Preclinical
Lead developer
Amorepacific Corporation
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Ginseng berry concentrate is a concentrated extract derived from the berry (fruit) of the Panax ginseng plant, distinct from the more commonly used root extract. Its major active constituents are ginsenosides, particularly ginsenosides Re and Rd, which are present in higher or unique amounts compared to ginseng root. Preclinical research indicates that ginseng berry concentrate exerts anti-proliferative and anti-inflammatory effects, notably in colorectal cancer models, primarily through cell cycle arrest (G2/M phase), induction of apoptosis, and downregulation of pro-inflammatory cytokines. It may also modulate immune responses by inhibiting Th17 cell differentiation. Ginseng berry concentrate is used and investigated as an herbal/dietary supplement, especially for its potential roles in immunostimulation, cancer chemoprevention, and anti-inflammatory effects. It is typically consumed orally. Evidence for clinical efficacy and safety remains limited. The product is not approved as a pharmaceutical drug and is primarily developed and marketed as a dietary supplement[3].

Other names
ginseng berry extractGBCPanax ginseng berry concentrate

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