Drug intelligence / Profile preview

ginseng G115

Development stage
Unknown
Lead developer
Pharmaton
Administration
Oral
01

Overview

Ginseng G115 is a **standardized extract of Panax ginseng**, derived from the root of the Asian/Korean ginseng plant and formulated to a precise, reproducible content of active compounds, primarily **ginsenosides**[2][5]. The extract is primarily standardized to a set ginsenoside content and is used mainly to support cognitive function, immune modulation, blood glucose regulation, and general physical endurance, though its efficacy for athletic performance is debated[1][2][3]. Research indicates that G115 can enhance immune responses, increase resistance to colds and influenza, modestly regulate blood glucose, and reduce subjective mental fatigue, with some studies pointing to improved cognitive performance[1][2][3]. The mechanism of action is thought to involve modulation of the hypothalamus-pituitary-adrenal axis, immunomodulation (enhancing natural killer and T helper cell activity), and glycemic control, largely mediated by the ginsenoside constituents[1][2][3]. G115 is considered **widely safe and well-tolerated** with mild and infrequent side effects[1][2][5]. Its efficacy as a supplement is supported by several decades of preclinical and clinical use, mainly in Europe and Asia.

Brand names
Ginsana
Other names
Panax ginseng extract G115standardized ginseng extract G115Panax ginseng G115Asian ginseng extract G115Chinese ginseng extract G115Korean ginseng extract G115
02

Targets

SIRT1 (NAD-dependent protein deacetylase sirtuin-1)AMPK (Adenosine monophosphate–activated protein kinase)ER (Estrogen receptor)

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