ginsenoside-Rp1

**Ginsenoside-Rp1** is a semi-synthesized derivative of ginsenoside Rg3, a saponin found in *Panax ginseng*. It is more stable and less toxic than Rg3 and exhibits strong anti-thrombotic, anti-inflammatory, and anti-tumor activities. Its mechanisms of action include inhibition of platelet activation (via the glycoprotein VI [GPVI] signaling pathway and suppression of ERK2 and p38 MAPK activation), attenuation of AKT and SIRT1 signaling implicated in multidrug resistance, and modulation of immune cell populations such as regulatory T cells (Tregs) and dendritic cells. Ginsenoside-Rp1 has demonstrated anti-metastatic and anti-inflammatory properties through NF-κB inhibition, and shows therapeutic potential for cardiovascular disorders, cancers (including colorectal and colon cancers), and inflammatory diseases[1][2][3][7][9][10][11].

Other names

ginsenoside-Rp1ginsenoside-Rp-1ginsenoside-Rp 1G-Rp1G-Rp-1G-Rp 1Rp1Rp-1Rp 1