Drug intelligence / Profile preview

giomer varnish

Development stage
Phase 4
Lead developer
SHOFU Dental
Modality
Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Dental
01

Overview

Giomer varnish is a bioactive, light-cured dental coating designed for the prevention and management of dentinal hypersensitivity and to promote remineralization of tooth structure. It incorporates Shofu Dental's proprietary Surface Pre-Reacted Glass (S-PRG) filler technology, which consists of multifunctional fluoro-boro-alumino-silicate glass particles surrounded by a glass-ionomer phase within a resin matrix. Upon application and curing, the varnish forms a protective barrier on exposed dentin or enamel that can last several months. The S-PRG fillers actively release and recharge six beneficial ions—fluoride, strontium, borate, aluminum, silicate, and sodium—which contribute to caries resistance by inhibiting plaque formation, neutralizing acids in the oral environment, promoting remineralization (including conversion to fluoroapatite/strontium apatite), and providing antibacterial effects. Giomer varnishes are primarily indicated for relief from hypersensitivity due to gingival recession or enamel loss but also serve as preventive agents against caries in high-risk patients due to their sustained ion release properties[2][3][5][6][10].

Brand names
PRG Barrier Coat
Other names
giomer-based light-curing varnishlight-cured Giomer varnishS-PRG-based varnish

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