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GIPR program (Structure Therapeutics)
- Development stage
- Preclinical
- Lead developer
- Structure Therapeutics
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
The GIPR program is an oral small-molecule drug candidate being developed by Structure Therapeutics (formerly ShouTi) for the treatment of obesity. It targets the Gastric Inhibitory Polypeptide Receptor (GIPR), a G protein-coupled receptor (GPCR) that plays a significant role in metabolic regulation, including insulin secretion and fat metabolism. By utilizing a structure-based drug discovery platform, the company aims to develop a potent oral alternative to existing injectable peptide-based GIPR modulators. The program is currently in the preclinical stage, and while its specific functional effect (agonism vs. antagonism) has not been publicly detailed in the provided context, it represents a key component of Structure Therapeutics' broader metabolic and obesity pipeline.
- Other names
- GIP receptor small molecule programShouTi GIPR program
02
Targets
GIPR (Gastric inhibitory polypeptide receptor)
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