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GKIND018A

Development stage: Preclinical
Lead developer: China Resources Guokang Pharmaceutical
Modality: Small Molecules

Overview

GKIND018A is a small molecule agonist of the 5-hydroxytryptamine receptor 4 (5-HT4) currently under development by China Resources Guokang Pharmaceutical. It is being investigated as a preclinical candidate for the treatment of adult chronic constipation. The mechanism of action involves the activation of 5-HT4 receptors in the gastrointestinal tract, which stimulates the release of acetylcholine and other neurotransmitters, thereby enhancing peristalsis and accelerating colonic transit.

Other names: GKIND018AGKIND-018AGKIND 018A

Targets

HTR4 (5-Hydroxytryptamine receptor 4)

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