glehnia littoralis extract

Glehnia littoralis extract (GLE) is a **natural plant extract** derived from *Glehnia littoralis*, a medicinal halophyte plant from the Apiaceae family. The extract is obtained primarily from the **leaves** and **roots** of the plant, though different extraction methods and plant parts may be used. GLE contains multiple **phenolic compounds** including quercetin, chlorogenic acid, and riboflavin, as well as **coumarins** (including pyranocoumarins and furanocoumarins such as imperatorin, psoralen, and bergapten), **lignanoids**, **flavonoids**, **terpenoids**, **polyacetylenes** (including falcarinol and panaxydiol), and other bioactive compounds[1][3]. The extract demonstrates **antioxidant** and **anti-inflammatory** properties through multiple mechanisms, including inhibition of COX-2, iNOS, and modulation of NF-κB and MAPK signaling pathways[1][2]. It has shown **neuroprotective effects** by upregulating BDNF and CREB expression, reducing acetylcholinesterase (AChE) activity, and promoting Nrf2/HO-1 signaling[2]. Traditional uses include treatment of **chronic bronchitis**, **immune-related diseases**, **fevers**, and **inflammation**[1][3][5]. The extract has been investigated for potential applications in **memory disorders**, **neuroinflammation**, **skin inflammation**, and as an **immunomodulatory agent**[1][2][3].

Other names

GLEGlehnia littoralis Fr. Schmidt ex Miq extractstandardized extract of Glehnia littoralis