Drug intelligence / Profile preview

GLK-40

Development stage
Preclinical
Lead developer
Glykos
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

GLK-40 is an antibody-drug conjugate (ADC) currently in the discovery phase of development by Glykos. It is being investigated for the treatment of various solid tumors. As an ADC, it is designed to utilize a monoclonal antibody to selectively deliver a cytotoxic payload to cancer cells, thereby minimizing systemic toxicity. The specific molecular target and the nature of the payload and linker technology used in GLK-40 have not been publicly disclosed by the sponsor.

02

Targets

TUBB (Tubulin (alpha and beta subunits))

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