Drug intelligence / Profile preview

Glubran Tiss 2

Development stage
Unknown
Lead developer
GEM
Modality
Small Molecules
Administration
Topical, Percutaneous
01

Overview

Glubran Tiss 2 is a sterile, two-component surgical adhesive and medical device composed of a blend of n-butyl cyanoacrylate (NBCA) and 2-octyl cyanoacrylate (OCA). This formulation is designed to provide a balance between high tensile strength (from NBCA) and elasticity (from OCA), making it suitable for both external skin wound closure and internal surgical applications, such as mesh fixation in laparoscopic and robotic hernia repairs. Upon contact with tissue moisture or hydroxide ions, the liquid monomers undergo an exothermic polymerization reaction to form a thin, flexible, and waterproof film that acts as a physical barrier with haemostatic and bacteriostatic properties. It is CE-marked as a Class IIa medical device and is often used in conjunction with the Glutack delivery system for precise application.

Brand names
Glubran Tiss 2
Other names
Glubran TissNBCA-OCA blend

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