Drug intelligence / Profile preview

glutathione + vitamin C

Development stage
Phase 2
Lead developer
TCI
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Oral, Intravenous, Topical, Intramuscular
01

Overview

Glutathione + vitamin C is a combination of two potent antioxidants used primarily as a dietary supplement. Glutathione is an endogenous tripeptide that plays a critical role in cellular detoxification, immune function, and protection against oxidative stress. Vitamin C (ascorbic acid) is an essential water-soluble vitamin involved in collagen synthesis, immune support, iron absorption, and also acts as a powerful antioxidant. When combined, these agents work synergistically to neutralize free radicals more effectively than either alone; vitamin C helps regenerate reduced glutathione levels within cells. This combination is widely marketed for skin health—particularly for reducing hyperpigmentation (melasma), lightening skin tone by inhibiting melanin production via tyrosinase suppression—and general anti-aging benefits due to their ability to reduce oxidative damage[3][4][5][6]. It may also be used as adjunctive therapy in chronic conditions associated with increased oxidative stress or nutritional deficiencies.

Brand names
Vedaneq L-Glutathione with Vitamin C for Skin & ImmunityAnola Perfect GlowL-Glutathione – 500 Mg + Vitamin C – 50 Mg
Other names
L-glutathione + ascorbic acidglutathione and vitamin C combination
02

Targets

DHAR/Grx (Dehydroascorbate reductase and related glutaredoxin/GSH-dependent reductases)GST (Glutathione S-transferase alpha 3)GPX4 (Glutathione peroxidase 4)TYR (Tyrosinase)

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