GLY 500

GLY 500 (also referred to as GLY-Lancet) is a branded generic formulation of metformin hydrochloride, an oral biguanide antihyperglycemic agent used for the management of type 2 diabetes mellitus. Marketed by Lancet Pharmaceuticals in India, it functions primarily by suppressing hepatic glucose production (gluconeogenesis) and increasing insulin-mediated glucose uptake in peripheral tissues such as skeletal muscle. At the molecular level, metformin activates AMP-activated protein kinase (AMPK) and inhibits mitochondrial respiratory chain complex I, leading to improved glycemic control without causing weight gain or hypoglycemia. It is a first-line therapeutic option for type 2 diabetes due to its established safety profile and efficacy in reducing HbA1c levels.

Brand names

GLY 500GLY500GLY-500GLY-Lancet

Other names

metformin hydrochloride