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glycerin + lidocaine hydrochloride anhydrous + benzalkonium chloride
- Development stage
- Unknown
- Lead developer
- Miles
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
A topical over-the-counter combination product containing **lidocaine hydrochloride anhydrous**, **benzalkonium chloride**, and **glycerin**. Lidocaine is a small-molecule local anesthetic that blocks voltage-gated sodium channels in peripheral sensory neurons to produce temporary topical analgesia and relief of pain and itching, while benzalkonium chloride is a quaternary ammonium antiseptic that disrupts microbial membranes and helps reduce risk of infection in minor wounds; glycerin functions primarily as a humectant and skin-conditioning excipient within the formulation. This combination is used for first-aid management of minor cuts, scrapes, burns, and related superficial skin irritation, and is marketed in topical formats such as spray, gel, and cream, with Bactine being the best-known U.S. brand associated with the lidocaine and benzalkonium combination.
- Brand names
- Bactine
- Other names
- glycerin + lidocaine hydrochloride anhydrous + benzalkoniumbenzalkonium chloride + lidocaine hydrochloridelidocaine hydrochloride + benzalkonium chloride + glycerin
02
Targets
NaV (Voltage-gated sodium channels)
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