glycerol + fructose

Glycerol + fructose is a combination pharmaceutical formulation used primarily for the treatment of elevated intracranial pressure and cerebral edema. The combination leverages the osmotic properties of both components to promote dehydration of brain tissue, thereby reducing intracranial pressure. Glycerol acts as an osmotic agent that draws water out from tissues into the bloodstream, while fructose serves as a carbohydrate source that can be metabolized via glycolysis and the tricarboxylic acid cycle. This combination is often administered intravenously in clinical settings for conditions such as cerebral hemorrhage with brain edema or other causes of increased intracranial pressure[1][2][3][7]. Clinical studies have shown significant improvement in neurological symptoms associated with high intracranial pressure following administration[1]. The formulation may also include sodium chloride to maintain electrolyte balance[1][6].

Brand names

Glyceol

Other names

glycerin and fructose injectionglycerol fructoseglycerin-fructose composition injection