Drug intelligence / Profile preview

glycerol monolaurate

Development stage
Preclinical
Lead developer
Daré Bioscience
Modality
Small Molecules
Administration
Vaginal
01

Overview

DARE-GML is a novel, multi-target antimicrobial formulation of glycerol monolaurate (GML) being developed by Daré Bioscience for the treatment of various vaginal health conditions, including bacterial, fungal, and viral infections. GML is a naturally occurring fatty acid ester that exhibits broad-spectrum antimicrobial activity by disrupting microbial cell membranes and inhibiting the production of inflammatory cytokines and exotoxins. Daré Bioscience acquired the exclusive global rights to develop and commercialize GML-based treatments from Hennepin Life Sciences in August 2022. The program is positioned as a potential first-in-category antimicrobial for conditions such as bacterial vaginosis and other intravaginal infections.

Other names
GMLmonolauringlycerin monolaurate1-lauroyl-sn-glycerol

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