glycerophosphoinositol

Glycerophosphoinositol is a naturally occurring, water-soluble metabolite of phosphoinositide hydrolysis by phospholipase A2 enzymes. It acts as a diffusible signaling molecule in eukaryotic cells, modulating key cell processes such as inflammation, proliferation, and actin cytoskeleton organization. In immune cells, glycerophosphoinositol limits inflammatory signaling—including NF-κB activation—and has been shown to reduce proinflammatory cytokine synthesis and thrombotic responses in preclinical models. It can act both intracellularly and in a paracrine manner, and its endogenous/exogenous administration has been studied for potential anti-inflammatory and anticancer effects[1][3][5].

Other names

GroPIns1-(sn-glycero-3-phospho)-1D-myo-inositol