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Glycine Buffer is an investigational inhaled diagnostic agent being developed by Case Western Reserve University to measure airway pH levels in patients with severe asthma and cystic fibrosis. The drug consists of an alkaline glycine buffer solution administered via inhalation. It is used in a Glycine Buffer Challenge test to non-invasively assess airway pH phenotypes, as lower airway pH is often associated with these respiratory conditions. By identifying specific pH phenotypes, clinicians can potentially develop more personalized treatment plans. The development is led by researchers at Case Western Reserve University School of Medicine and University Hospitals Rainbow Babies & Children's Hospital.
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