Drug intelligence / Profile preview

glycine propionyl-L-carnitine

Development stage
Preclinical
Lead developer
Sigma-Tau HealthScience
Modality
Small Molecules
Administration
Oral
01

Overview

Glycine propionyl-L-carnitine is a dietary supplement consisting of a molecularly bonded combination of propionyl-L-carnitine and the amino acid glycine. It acts as a prodrug, leading to increased levels of glycine, carnitine, and propionic acid in the body. Its main investigated effects are as a nitric oxide stimulant (increasing blood nitrate/nitrite, a surrogate marker of nitric oxide), antioxidant (reducing lipid peroxidation), and as a potential ergogenic aid to enhance anaerobic power output and reduce exercise-related lactate buildup. Research suggests its vasodilatory and potential antioxidant properties may improve blood flow and reduce oxidative stress during and after strenuous exercise. GPLC is mainly marketed and used as a dietary supplement, especially among athletes and those aiming to improve exercise performance or vascular health[1][5][7][9].

Other names
Glycine Propionyl-L-Carnitine HClGlycine Propionyl-L-Carnitine Hydrochloride
02

Targets

NOS3 (eNOS)Carnitine metabolic enzymes

Beyond the preview

Go deeper on glycine propionyl-L-carnitine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on glycine propionyl-L-carnitine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call