Drug intelligence / Profile preview

GlycoAla

Development stage
Unknown
Lead developer
Z-COSMETICS
Modality
Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Topical
01

Overview

GlycoAla is a topical photodynamic skin care treatment that utilizes a proprietary glycosphere (liposomal) delivery system to encapsulate 5-aminolevulinic acid (5-ALA). It is primarily indicated for the aesthetic improvement of sun-damaged skin, fine lines, uneven skin tone, and acne-prone skin. Upon topical application, the 5-ALA is absorbed into the skin and metabolized into protoporphyrin IX (PpIX), a potent photosensitizing agent. When activated by specific wavelengths of light (such as LED or IPL), PpIX triggers a photodynamic reaction that generates reactive oxygen species, leading to selective cellular rejuvenation and the targeting of damaged skin structures. The glycosphere technology is designed to enhance the stability and penetration of 5-ALA while minimizing the irritation and downtime typically associated with high-concentration photodynamic therapy (PDT) agents.

Brand names
GlycoAla
Other names
GlycoAla Photodynamic Gel5-aminolevulinic acid glycosphere

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