glycyrrhiza inflata extract

glycyrrhiza inflata extract is a plant-derived extract obtained from the roots of Glycyrrhiza inflata (a species of licorice). A specialized formulation of this extract, known as AD-lico/Healthy Gut, is under clinical development by ADbiotech for the treatment of gastrointestinal diseases and inflammatory bowel disease. The extract contains key bioactive components such as licochalcone A, liquiritigenin, licochalcone E, glycyrrhizin, and glabridin. It has been shown to exhibit anti-inflammatory, gastroprotective, and gastric-relaxing effects, including the reduction of inflammatory markers like iNOS and COX-2, and the inhibition of Helicobacter pylori mucosal damage. The formulation is specifically prepared to minimize glycyrrhizin levels, thereby reducing potential side effects such as hypokalemia and muscle weakness. Additionally, components of the extract have demonstrated potential in suppressing aromatase expression and activity, suggesting a role in breast cancer chemoprevention [2566].

Brand names

Healthy Gut

Other names

Glycyrrhiza inflata extractlicorice extract