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glycyrrhizae decoction for clearing stomach-fire
- Development stage
- Unknown
- Lead developer
- First Affiliated Hospital of Henan University of Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Glycyrrhizae Decoction for Clearing Stomach-Fire is a traditional Chinese medicine (TCM) formula developed by The First Affiliated Hospital of Henan College of TCM. It is specifically investigated for the treatment of recurrent oral ulcers in patients with HIV infection or AIDS, particularly those diagnosed with the TCM syndrome of dampness-heat of the spleen and stomach. The decoction is designed to 'clear stomach-fire,' a concept in TCM associated with reducing inflammation and heat in the upper digestive tract, thereby promoting the healing of oral mucosal lesions. In clinical pre-tests, it has been evaluated for safety and efficacy compared to standard treatments like levamisole and vitamins.
- Other names
- Glycyrrhizae Decoction for Puring Stomach-Fire
02
Targets
MEKESR1 (ERα)HSD11B2 (11β-HSD2)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)ESR2 (ERβ)
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