Drug intelligence / Profile preview

GO6979

Development stage
Unknown
Modality
Small Molecules
Administration
In Vitro, In Vivo (animal Model, Injectable; Not For Clinical Purposes)
01

Overview

GO6979 is a **synthetic small molecule inhibitor** primarily used in research to **inhibit specific isoforms of protein kinase C (PKC)**, with notable activity against **PKC-alpha and PKC-beta**. It is frequently used as a **biochemical tool** to study PKC-dependent signaling pathways, cell migration, differentiation, and function in cell and animal models. GO6979 is not approved for clinical or therapeutic use in humans; its use is restricted to laboratory research applications. Mechanistically, GO6979 is a **selective ATP-competitive inhibitor** of PKC, blocking kinase activity and downstream cellular responses involved in immune signaling, cancer biology, angiogenesis, and inflammation[3][7].

02

Targets

PRKCB (Protein kinase C beta)PRKCA (Protein kinase C alpha)PRKCZ (Protein kinase C zeta)

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