Drug intelligence / Profile preview

golden berry seed extract

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Golden berry seed extract is a bioactive lipid fraction derived from the seeds of *Physalis peruviana*, a plant native to the high-altitude regions of the Andes. The extract is characterized by a high concentration of essential fatty acids, particularly linoleic acid (omega-6), and is a rich source of phytosterols (such as beta-sitosterol, campesterol, and stigmasterol) and tocopherols (Vitamin E). In biotechnology and nutritional science, it is valued for its potent antioxidant and anti-inflammatory properties. The mechanism of action involves the neutralization of reactive oxygen species (ROS) by tocopherols and the modulation of inflammatory signaling pathways by phytosterols and withanolides, which may inhibit pro-inflammatory enzymes like cyclooxygenase-2 (COX-2). It is primarily utilized as a dietary supplement for cardiovascular and metabolic health and as a topical agent in dermatological formulations to enhance skin barrier function and protect against oxidative damage.

Other names
Physalis peruviana seed extractCape gooseberry seed extractInca berry seed extractgolden berry seed oil
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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