goldenseal

Goldenseal (Hydrastis canadensis) is a perennial herb native to North America and widely used in traditional medicine. Its primary active compound is berberine[1][3], which exhibits antimicrobial activity against bacteria and fungi in vitro. Goldenseal has been traditionally used for digestive disorders, skin and eye conditions[2], wounds[7], infections of various types[5], and as an insect repellent and diuretic. It may also have effects on cardiovascular health and cancer risk according to some sources[7]. Mechanistically, berberine from goldenseal inhibits cytochrome P450 enzymes CYP3A4 and CYP2D6 in the liver[5], potentially affecting the metabolism of many pharmaceutical drugs. Goldenseal is primarily available as a dietary supplement in forms such as dried root/rhizome powder or liquid extract.

Other names

eyebalmeyerootgoldenrootground raspberryindian turmericjaundice rootorangerootradix hydrastissceau d'oryellow puccoonyellowroot