gonadotropin-releasing hormone + human menopausal gonadotropin + human chorionic gonadotropin + progesterone

This is a combination therapy consisting of four hormones commonly used in assisted reproductive technology (ART) and fertility treatments: - **Gonadotropin-releasing hormone (GnRH):** A hypothalamic peptide that regulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary, controlling ovarian stimulation and ovulation timing[4]. - **Human menopausal gonadotropin (hMG):** Contains both FSH and LH, purified from the urine of postmenopausal women. It stimulates ovarian follicle development in women with infertility due to anovulation or other causes[1][3][6][8]. - **Human chorionic gonadotropin (hCG):** Mimics the natural LH surge to trigger final oocyte maturation and ovulation after controlled ovarian stimulation. It also supports corpus luteum function for early pregnancy maintenance[7]. - **Progesterone:** A steroid hormone essential for preparing the endometrium for implantation and maintaining early pregnancy. This multi-hormonal regimen is typically used as part of complex fertility protocols such as in vitro fertilization (IVF), where precise control over ovulation induction, egg maturation, luteal support, and synchronization with embryo transfer are required. Each component plays a distinct role at different stages of the cycle to maximize chances of successful conception.