Drug intelligence / Profile preview

gonadotropin-releasing hormone agonist + polyethylene glycol + Rh760

Development stage
Preclinical
Lead developer
Anhui Guoping Pharmaceutical
Modality
Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intravenous, Intraperitoneal
01

Overview

This product is a **combination formulation** comprised of a gonadotropin-releasing hormone agonist (a class of peptide hormone drugs that target the gonadotropin-releasing hormone receptor to modulate reproductive hormone secretion), polyethylene glycol (an inert polymer often used to improve pharmacokinetics or solubility), and Rh760 (a near-infrared fluorescent dye, specifically in the context of FSH-Rh760, for imaging and photothermal therapy in oncology)[1]. While the specific formulation requested (gonadotropin-releasing hormone agonist + polyethylene glycol + Rh760) is not directly described in clinical literature, compounds containing Rh760 are used as targeted imaging agents, leveraging peptide conjugates (e.g. FSH peptide–Rh760) for **tumor-specific imaging and photothermal therapy**, particularly in ovarian cancer.

02

Targets

GnRHR (Gonadotropin-releasing hormone receptor)

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