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Gonolobus condurango is a tropical climbing vine native to the Andes of Ecuador, Peru, and Colombia. The dried bark of its branches and trunk is used in traditional herbal medicine, primarily as a digestive aid and appetite stimulant. It has been historically used for indigestion, stomach cancer, chronic gastritis, peptic ulcers, skin ulcers, chronic anemia, syphilis (as an alterative), rheumatism, neuralgia, and as an analgesic and tonic. Its mechanism is thought to involve stimulation of saliva and gastric juices due to bitter constituents such as tannins and alkaloids (one resembling strychnine). While it was once considered a potential remedy for early-stage stomach cancer or tumors in animals—and included in pharmacopeias in the late 19th century—there is no reliable scientific evidence supporting its effectiveness for any indication. It remains available mainly as a homeopathic or herbal supplement[1][2][3][4][5][6][8].
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