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GORD167 is a bispecific antibody being developed by Gordion Bioscience to treat tumors that are non-responsive to standard PD-L1 checkpoint inhibitor therapies. Developed using the company's machine learning platform and patient-derived tumor genomic data, the antibody is designed to simultaneously inhibit primary drug targets and their compensatory resistance mechanisms. While the specific molecular targets remain undisclosed, the therapeutic strategy focuses on overcoming mechanisms of resistance in PD-L1 non-responding patients. GORD167 is currently in Phase 1 clinical development.
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