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goupi gao
- Development stage
- Unknown
- Lead developer
- Beijing Tong Ren Tang
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Topical
01
Overview
Goupi Gao is a classic traditional Chinese medicine (TCM) black plaster formulation used for external application. Historically utilized since the Tang and Song Dynasties, it is composed of a complex mixture of herbal extracts processed within a vegetable oil and lead oxide matrix, creating a unique double continuous phase system with soap crystal fibers. It is primarily indicated for the treatment of conditions associated with 'cold blood stasis,' including knee osteoarthritis, rheumatism, and musculoskeletal pain. The formulation provides a slow-release delivery of active components such as cinnamaldehyde and eugenol, and is characterized by its strong adhesion and stability across varying temperatures.
- Brand names
- Goupi Gao
- Other names
- Dog Skin PlasterGoupi PlasterBlack PlasterHei Gao Yao
02
Targets
TRPA1 (Transient receptor potential cation channel subfamily A member 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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