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GPR110 siRNA is a research-grade small interfering RNA (siRNA) reagent designed to knock down the expression of the GPR110 (ADGRF1) gene, which encodes an adhesion G protein-coupled receptor. It is primarily used as a laboratory tool in preclinical research to investigate the biological roles of GPR110. Studies have utilized GPR110 siRNA to explore its involvement in HER2-positive breast cancer tumorigenesis, metastasis, and drug resistance, as well as in metabolic-associated steatohepatitis (MASH) mouse models.
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