Drug intelligence / Profile preview

Gproan Combined HFMD Vaccine

Development stage
Preclinical
Lead developer
Sinovac Biotech
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

Gproan Combined HFMD Vaccine is a bivalent recombinant protein subunit vaccine being developed by Gproan Biotech for the prevention of Hand-Foot-and-Mouth Disease (HFMD). The vaccine candidate is designed to provide broad protection by targeting the two most common and severe causative agents of HFMD: Enterovirus 71 (EV71) and Coxsackievirus A16 (CoxA16). By utilizing recombinant viral capsid proteins as antigens, the vaccine aims to stimulate a robust neutralizing antibody response without the risks associated with live-attenuated or inactivated whole-virus vaccines. Currently in preclinical development, this combined subunit approach represents a strategic effort to address the multi-etiological nature of HFMD outbreaks, particularly in pediatric populations across the Asia-Pacific region.

Other names
EV71-CoxA16 recombinant protein subunit vaccineEV-71-CoxA16 recombinant protein subunit vaccineEV 71-CoxA16 recombinant protein subunit vaccineGproan HFMD vaccineCombined HFMD Vaccine (EV71+CoxA16)
02

Targets

CA16 (Coxsackievirus A16)

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