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Drug intelligence / Profile preview
GQ1012
- Development stage
- Preclinical
- Lead developer
- GeneQuantum Biosciences
- Modality
- Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
01
Overview
GQ1012: sourced facts only. name: "Validation of the iGDC platform is exemplified by GQ1012, a HER2-targeting ADC featuring the potent Topoisomerase I inhibitor, TopoIx." [DOI:10.1158/1538-7445.am2024-2124]; target: "Validation of the iGDC platform is exemplified by GQ1012, a HER2-targeting ADC featuring the potent Topoisomerase I inhibitor, TopoIx." [DOI:10.1158/1538-7445.am2024-2124]; developer: "1GeneQuantum Healthcare (Suzhou) Co., Ltd., Suzhou, China." [DOI:10.1158/1538-7445.am2024-2124]; modality: "Validation of the iGDC platform is exemplified by GQ1012, a HER2-targeting ADC featuring the potent Topoisomerase I inhibitor, TopoIx." [DOI:10.1158/1538-7445.am2024-2124]; stage: "In various in vivo models, GQ1012 demonstrated similar or superior antitumor efficacy compared to Enhertu, showcasing strong synergy with anti-PD-1 therapy." [DOI:10.1158/1538-7445.am2024-2124]
02
Targets
ERBB2 (Erb-b2 receptor tyrosine kinase 2)
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