Drug intelligence / Profile preview

Granu Fink Prosta forte

Development stage
Unknown
Lead developer
Perrigo
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Granu Fink Prosta forte is a traditional herbal medicine (phytomedicine) containing a thick extract of pumpkin seeds (*Cucurbitae semen*). It is specifically indicated for the treatment of lower urinary tract symptoms (LUTS) in adult men, particularly those associated with benign prostatic hyperplasia (BPH) stages I to II (per Alken) or II to III (per Vahlensieck). The primary bioactive components are prostate-active Delta-7 sterols (Δ7-sterols), which exhibit structural similarities to the androgen dihydrotestosterone (DHT), allowing them to target the prostate/androgen signaling pathway. Marketed as hard capsules, the drug has been acknowledged by EAU Guidelines for long-term efficacy and has been evaluated in observational studies for its ability to improve symptoms such as frequent urination, nocturia, and weak urine stream.

Brand names
Granu Fink Prosta forte
Other names
pumpkin seed extractCucurbitae semen extract
02

Targets

SRD5A (Steroid 5-alpha-reductase)AR (Adrenergic receptors)

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