grazax

Grazax is a sublingual immunotherapy tablet containing a standardized allergen extract of Timothy grass pollen (Phleum pratense). It is indicated for the disease-modifying treatment of grass pollen-induced allergic rhinitis and/or conjunctivitis in adults, adolescents, and children aged 5 years and older. Grazax works by exposing the immune system to controlled amounts of the specific allergen, thereby inducing immunological tolerance over time. This process leads to an increase in specific IgG4 antibodies that compete with IgE for binding to allergens, reducing allergic symptoms upon subsequent exposure. The exact mechanism is not fully understood but involves modulation of immune responses against grass pollen allergens[3][8]. Treatment typically lasts three years and has demonstrated sustained clinical benefit after discontinuation[8].

Brand names

Grazax

Other names

Phleum pratense allergen extractgrass pollen allergen extract (Phleum pratense)Timothy grass pollen allergen extract