Drug intelligence / Profile preview

Green coffee bean extract

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Green coffee bean extract is derived from unroasted seeds of the *Coffea* plant (primarily *Coffea arabica* and *Coffea canephora*). It contains higher levels of chlorogenic acids compared to roasted coffee beans. The main active compounds are chlorogenic acids and caffeine. Chlorogenic acids are believed to have antioxidant properties and may influence glucose metabolism and fat absorption, potentially contributing to weight management. Caffeine acts as a central nervous system stimulant. Green coffee bean extract is primarily marketed as a dietary supplement for weight loss and general health benefits such as blood pressure reduction and antioxidant support[2][3][4][5]. There is no established pharmaceutical developer; it is produced by various supplement manufacturers.

Brand names
Svetol
Other names
Green coffeeGreen coffee extractCoffea arabica extractCoffea canephora extract
02

Targets

ADORA2A (Adenosine A₂A Receptor)ADORA3 (Adenosine A3 receptor)ADORA2B (Adenosine A2B receptor)ADORA1 (Adenosine receptor A1 subtype)SLC superfamily (Solute carrier superfamily)

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