Drug intelligence / Profile preview

green propolis

Development stage
Phase 2
Lead developer
Apis Flora
Modality
Small Molecules
Administration
Oral, Topical, Buccal
01

Overview

Green propolis is a natural resinous substance collected by honeybees (*Apis mellifera*) from specific botanical sources, primarily *Baccharis dracunculifolia* in Brazil and *Macaranga tanarius* in Taiwan. It is chemically distinct from other propolis types due to its high concentration of bioactive compounds such as prenylated flavanones (propolins C, D, F, G, and H) in the Taiwanese variety and artepillin C, p-coumaric acid, and caffeic acid in the Brazilian variety. Green propolis exhibits a broad range of pharmacological activities, including anti-inflammatory, antioxidant, immunomodulatory, and antimicrobial effects. Clinical investigations have explored its potential in managing metabolic dysfunction-associated steatotic liver disease (MASLD), dyslipidemia, oral mucositis in cancer patients, and as an adjunct treatment for COVID-19 and chronic kidney disease-related inflammation.

Other names
Taiwanese green propolisBrazilian green propolisTGPBGPpropolis extract
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

Beyond the preview

Go deeper on green propolis.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on green propolis.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call