Drug intelligence / Profile preview

GreenGene F

Development stage
Phase 3
Lead developer
GC Biopharma
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

GreenGene F is a recombinant coagulation factor VIII replacement therapy for **hemophilia A**, developed by **GC Biopharma**. Available evidence identifies it as **beroctocog alfa**, a **third-generation recombinant human factor VIII** product; published characterization describes it as a **B-domain deleted FVIII protein**. Its therapeutic mechanism is straightforward factor replacement: infused FVIII restores deficient coagulation factor VIII activity, enabling formation of the intrinsic tenase complex and improving thrombin generation and hemostasis in patients with hemophilia A. Clinical development included at least phase 3 and extension studies in previously treated patients with severe hemophilia A, and public reporting indicates approval in China for hemophilia A.

Brand names
GreenGene F
Other names
GreenGene\u2122 Fberoctocog alfa
02

Targets

F8 (Coagulation Factor VIIIa)

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