Drug intelligence / Profile preview

Greenplast Q

Development stage
Unknown
Lead developer
GC Biopharma
Modality
Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

Greenplast Q is a human-derived fibrin sealant (fibrin glue) developed by GC Biopharma and evaluated by Seoul National University Hospital for the prevention of iatrogenic ulcer bleeding. It is a combination product containing human fibrinogen concentrate, human thrombin, aprotinin (a fibrinolysis inhibitor), and calcium chloride. When applied topically to a wound or surgical site, the thrombin converts the fibrinogen into fibrin, creating a stable clot that mimics the final stage of the natural coagulation cascade. This provides immediate hemostasis and supports tissue sealing. In clinical trials, it is specifically being evaluated for its efficacy in reducing post-procedural bleeding in high-risk patients undergoing endoscopic submucosal dissection (ESD) for gastric neoplasms.

Brand names
Greenplast Q
Other names
human fibrinogen concentratefibrin gluefibrin sealant
02

Targets

PLG (Plasminogen)F2 (Thrombin)FXIIIa (Coagulation factor XIII A subunit)

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