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GRI-0729 is a preclinical-stage type 2 Natural Killer T (NKT) cell agonist being developed by GRI Bio. The compound is designed to modulate the immune system by activating type 2 NKT cells, which play a regulatory role in balancing inflammatory immune responses. GRI Bio is focusing on the development of this asset for the treatment of various inflammatory, fibrotic, and autoimmune diseases. The program is part of a broader pipeline of NKT cell modulators that includes GRI-0621 (a type 1 NKT antagonist) and other type 2 NKT agonists like GRI-0124.
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