Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Grippferon with loratadine
- Development stage
- Unknown
- Lead developer
- Firn-M
- Modality
- Small Molecules, Recombinant Proteins and Enzymes
- Administration
- Intranasal
01
Overview
Grippferon with loratadine is a combination nasal ointment developed and manufactured by Firn M for the prevention and treatment of influenza and acute respiratory viral infections (ARVI), particularly in patients with allergic rhinitis. The formulation combines recombinant human interferon alfa-2b with loratadine, a second-generation antihistamine. The interferon component binds to the interferon alpha/beta receptor (IFNAR), triggering a signaling cascade that induces antiviral and immunomodulatory effects to combat viral replication. Loratadine acts as a selective histamine H1 receptor antagonist, which reduces allergic symptoms and prevents nasal mucosal edema, addressing the increased susceptibility to respiratory infections often seen in patients with allergic diseases. The drug is approved in Russia for use in adults and is applied intranasally.
- Brand names
- Grippferon with loratadineГриппферон с лоратадином
- Other names
- interferon alfa-2b + loratadine
02
Targets
HRH1 (Histamine H1 Receptor)IFNAR (Immune system modulation via type I interferon receptor)
Beyond the preview
Go deeper on Grippferon with loratadine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Grippferon with loratadine.