Drug intelligence / Profile preview

Grippostad Complex

Development stage
Phase 3
Lead developer
STADA
Modality
Small Molecules
Administration
Oral
01

Overview

Grippostad Complex is an over-the-counter combination medication developed by STADA Arzneimittel for the symptomatic treatment of rhinosinusitis, pain, and fever associated with the common cold and flu-like symptoms. It contains acetylsalicylic acid (ASA), which acts as an analgesic, antipyretic, and anti-inflammatory agent by inhibiting prostaglandin G/H synthase 1 (COX-1) and 2 (COX-2), and pseudoephedrine hydrochloride, a nasal decongestant that acts as an agonist on alpha- and beta-adrenergic receptors to reduce nasal mucosal swelling. The product is formulated as granules for oral suspension and is intended for adults and adolescents aged 16 years and older.

Brand names
Grippostad Complex
Other names
acetylsalicylic acid + pseudoephedrine hydrochloride
02

Targets

ADRA1A (α1A)ADRA2A (α2A)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ADRA1 (Alpha-1 adrenergic receptor family)ADRB1 (β1)

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