Drug intelligence / Profile preview

GRK006

Development stage
Preclinical
Lead developer
Suzhou Glanke Medical Technology
Modality
Small Molecules
Administration
Intravenous
01

Overview

GRK006 is an investigational small molecule therapeutic candidate being developed by Suzhou Glanke Medical Technology (GrandKol) for the treatment of traumatic brain injury (TBI). The drug is designed to block a specific cell death channel that is activated following brain trauma, thereby protecting neurons from injury-induced cell death. GRK006 is intended for intravenous (IV) administration during the acute phase of brain injury, with potential applications in treating injuries resulting from motor vehicle accidents, sports-related impacts, falls, and battlefield blast-induced trauma.

02

Targets

TRPM4 (Calcium-activated non-selective cation channel TRPM4)

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