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Drug intelligence / Profile preview
gross thymic extract
- Development stage
- Preclinical
- Lead developer
- YS Nature Company
- Modality
- Recombinant Proteins and Enzymes, Peptides
- Administration
- Oral
01
Overview
Gross thymic extract (GTE), marketed under the brand name Thymax, is an orally active, porcine-derived biological extract composed of thymosin, thymomodulin, and other heat-resistant peptides prepared at an acidic pH. Developed by YS Nature Company, GTE acts as a biological response modifier with immunomodulatory and potential antineoplastic properties. It has been shown to induce cell cycle arrest (G0/G1 phase) and trigger apoptosis via the intrinsic mitochondrial pathway in various cancer models, including breast cancer and leukemia. Additionally, GTE enhances immune function by activating dendritic cells, promoting Th1-directed T-cell responses, and increasing natural killer (NK) cell cytotoxicity.
- Brand names
- Thymax
- Other names
- gross thymus extract
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