group LV-Seoul National University Hospital

group LV-Seoul National University Hospital refers to a specific treatment arm in a clinical trial conducted by Seoul National University Hospital investigating the blunting of hemodynamic responses during endotracheal intubation. In this protocol, a 10% lidocaine spray is applied topically to both the laryngoscope blade and the tracheal mucosa prior to intubation. Lidocaine is a local anesthetic that functions by blocking voltage-gated sodium channels, thereby inhibiting the conduction of nerve impulses from sensory neurons. By anesthetizing the airway and providing lubrication, this intervention aims to minimize the sympathetic surge (tachycardia and hypertension) associated with airway manipulation in neurosurgical patients undergoing anesthesia induction with propofol and remifentanil.

Other names

10% lidocaine spraylidocaine spray