Drug intelligence / Profile preview

growth hormone + liraglutide

Development stage
Phase 4
Lead developer
Novo Nordisk
Modality
Recombinant Proteins and Enzymes, Peptides
Administration
Subcutaneous
01

Overview

A combination of growth hormone (GH) and liraglutide being investigated for potential effects on metabolism and diabetes management. Growth hormone is a peptide hormone that stimulates growth, cell reproduction, and regeneration, while liraglutide is a GLP-1 receptor agonist used for treating type 2 diabetes and obesity. Research has shown that while liraglutide significantly reduces food intake, improves glucose tolerance, and enhances insulin sensitivity, the addition of growth hormone does not significantly augment these beneficial effects in experimental models.

02

Targets

GLP1R (GLP-1R)GHR (Growth hormone receptor)

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